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BMCBI
2010
14 years 9 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
BMCBI
2007
14 years 9 months ago
2007
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
BMCBI
2008
14 years 9 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
BMCBI
2008
14 years 9 months ago
2008
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
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BMCBI
2008
14 years 9 months ago
2008
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...