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135
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BMCBI
2010
126views more  BMCBI 2010»
15 years 2 months ago
A boosting method for maximizing the partial area under the ROC curve
Background: The receiver operating characteristic (ROC) curve is a fundamental tool to assess the discriminant performance for not only a single marker but also a score function c...
Osamu Komori, Shinto Eguchi
BMCBI
2007
95views more  BMCBI 2007»
15 years 2 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
116
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 2 months ago
FCI: an R-based algorithm for evaluating uncertainty of absolute real-time PCR quantification
Background: FCI is an R code for analyzing data from real-time PCR experiments. This algorithm estimates standard curve features as well as nucleic acid concentrations and confide...
Paolo Verderio, Sara Pizzamiglio, Fabio Gallo, Sim...
BMCBI
2008
118views more  BMCBI 2008»
15 years 2 months ago
Kismeth: Analyzer of plant methylation states through bisulfite sequencing
Background: There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will sh...
Eyal Gruntman, Yijun Qi, R. Keith Slotkin, Ted Roe...
BMCBI
2008
128views more  BMCBI 2008»
15 years 2 months ago
HAPSIMU: a genetic simulation platform for population-based association studies
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
Feng Zhang, Jianfeng Liu, Jie Chen, Hong-Wen Deng