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» Smoothing Gene Expression Using Biological Networks
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BMCBI
2010
152views more  BMCBI 2010»
13 years 6 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
JCB
2007
198views more  JCB 2007»
13 years 6 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
GECCO
2009
Springer
130views Optimization» more  GECCO 2009»
14 years 24 days ago
Liposome logic
VLSI research, in its continuous push toward further miniaturisation, is seeking to break through the limitations of current circuit manufacture techniques by moving towards biomi...
James Smaldon, Natalio Krasnogor, Alexander Camero...
BMCBI
2010
156views more  BMCBI 2010»
13 years 6 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
CMSB
2010
Springer
13 years 1 months ago
Stochasticity in reactions: a probabilistic Boolean modeling approach
Boolean modeling frameworks have long since proved their worth for capturing and analyzing essential characteristics of complex systems. Hybrid approaches aim at exploiting the ad...
Sven Twardziok, Heike Siebert, Alexander Heyl