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BMCBI
2011
14 years 1 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
BMCBI
2006
153views more  BMCBI 2006»
14 years 9 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
KDD
2001
ACM
142views Data Mining» more  KDD 2001»
15 years 10 months ago
TreeDT: gene mapping by tree disequilibrium test
We introduce and evaluate TreeDT, a novel gene mapping method which is based on discovering and assessing tree-like patterns in genetic marker data. Gene mapping aims at discoveri...
Petteri Sevon, Hannu Toivonen, Vesa Ollikainen
BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
IPMI
2007
Springer
15 years 10 months ago
Inter and Intra-modal Deformable Registration: Continuous Deformations Meet Efficient Optimal Linear Programming
In this paper we propose a novel non-rigid volume registration based on discrete labeling and linear programming. The proposed framework reformulates registration as a minimal path...
Ben Glocker, Nikos Komodakis, Nikos Paragios, Geor...