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» Some Observations on Indifferentiability
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BMCBI
2008
96views more  BMCBI 2008»
14 years 11 months ago
Novel methodology for construction and pruning of quasi-median networks
Background: Visualising the evolutionary history of a set of sequences is a challenge for molecular phylogenetics. One approach is to use undirected graphs, such as median network...
Sarah C. Ayling, Terence A. Brown
BMCBI
2007
156views more  BMCBI 2007»
14 years 11 months ago
Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
BMCBI
2007
153views more  BMCBI 2007»
14 years 11 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
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BMCBI
2007
97views more  BMCBI 2007»
14 years 11 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2007
114views more  BMCBI 2007»
14 years 11 months ago
False occurrences of functional motifs in protein sequences highlight evolutionary constraints
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
Allegra Via, Pier Federico Gherardini, Enrico Ferr...