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» Some Observations on Indifferentiability
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BMCBI
2008
95views more  BMCBI 2008»
14 years 11 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2008
142views more  BMCBI 2008»
14 years 11 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
139views more  BMCBI 2008»
14 years 11 months ago
The C1C2: A framework for simultaneous model selection and assessment
Background: There has been recent concern regarding the inability of predictive modeling approaches to generalize to new data. Some of the problems can be attributed to improper m...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2008
71views more  BMCBI 2008»
14 years 11 months ago
A tale of two symmetrical tails: Structural and functional characteristics of palindromes in proteins
Background: It has been previously shown that palindromic sequences are frequently observed in proteins. However, our knowledge about their evolutionary origin and their possible ...
Armita Sheari, Mehdi Kargar, Ali Katanforoush, Sha...
BMCBI
2008
137views more  BMCBI 2008»
14 years 11 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...