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» Some Observations on Indifferentiability
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BMCBI
2006
78views more  BMCBI 2006»
14 years 11 months ago
Modelling study of dimerization in mammalian defensins
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
Anita Suresh, Chandra Verma
BMCBI
2006
202views more  BMCBI 2006»
14 years 11 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
BMCBI
2006
103views more  BMCBI 2006»
14 years 11 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
BMCBI
2006
116views more  BMCBI 2006»
14 years 11 months ago
ROKU: a novel method for identification of tissue-specific genes
Background: One of the important goals of microarray research is the identification of genes whose expression is considerably higher or lower in some tissues than in others. We wo...
Koji Kadota, Jiazhen Ye, Yuji Nakai, Tohru Terada,...
BMCBI
2006
150views more  BMCBI 2006»
14 years 11 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils