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» Some Results on Orthogonal Factorizations
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BMCBI
2010
95views more  BMCBI 2010»
14 years 9 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2008
90views more  BMCBI 2008»
14 years 9 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
BMCBI
2010
86views more  BMCBI 2010»
14 years 9 months ago
The oligodeoxynucleotide sequences corresponding to never-expressed peptide motifs are mainly located in the non-coding strand
Background: We study the usage of specific peptide platforms in protein composition. Using the pentapeptide as a unit of length, we find that in the universal proteome many pentap...
Giovanni Capone, Giuseppe Novello, Candida Fasano,...
CSSC
2008
110views more  CSSC 2008»
14 years 9 months ago
Bayesian False Discovery Rate Wavelet Shrinkage: Theory and Applications
The interest in inference in the wavelet domain remains vibrant area of statistical research because of needs of scientific community to process and explore massive data sets. Prim...
Ilya Lavrik, Yoon Young Jung, Fabrizio Ruggeri, Br...