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BMCBI
2008
176views more  BMCBI 2008»
15 years 1 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2008
137views more  BMCBI 2008»
15 years 1 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...
BMCBI
2008
119views more  BMCBI 2008»
15 years 1 months ago
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
BMCBI
2008
102views more  BMCBI 2008»
15 years 1 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
BMCBI
2008
122views more  BMCBI 2008»
15 years 1 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
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