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BMCBI
2004
158views more  BMCBI 2004»
15 years 1 months ago
Incremental genetic K-means algorithm and its application in gene expression data analysis
Background: In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms suc...
Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, ...
BMCBI
2004
96views more  BMCBI 2004»
15 years 1 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2004
117views more  BMCBI 2004»
15 years 1 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
BMCBI
2004
177views more  BMCBI 2004»
15 years 1 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2004
123views more  BMCBI 2004»
15 years 1 months ago
A two-way interface between limited Systems Biology Markup Language and R
Background: Systems Biology Markup Language (SBML) is gaining broad usage as a standard for representing dynamical systems as data structures. The open source statistical programm...
Tomas Radivoyevitch
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