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BMCBI
2005
158views more  BMCBI 2005»
14 years 9 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
BMCBI
2005
113views more  BMCBI 2005»
14 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2005
94views more  BMCBI 2005»
14 years 9 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
BMCBI
2005
87views more  BMCBI 2005»
14 years 9 months ago
BioCreAtIvE Task 1A: gene mention finding evaluation
Background: The biological research literature is a major repository of knowledge. As the amount of literature increases, it will get harder to find the information of interest on...
Alexander S. Yeh, Alexander A. Morgan, Marc E. Col...
BMCBI
2005
117views more  BMCBI 2005»
14 years 9 months ago
An evaluation of GO annotation retrieval for BioCreAtIvE and GOA
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
Evelyn Camon, Daniel Barrell, Emily Dimmer, Vivian...
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