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BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2007
171views more  BMCBI 2007»
14 years 9 months ago
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed,
Background: Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a...
Wei Yu, Ajay Yesupriya, Anja Wulf, Junfeng Qu, Mui...
BMCBI
2007
94views more  BMCBI 2007»
14 years 9 months ago
False positive reduction in protein-protein interaction predictions using gene ontology annotations
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Mahmood A. Mahdavi, Yen-Han Lin
BMCBI
2007
119views more  BMCBI 2007»
14 years 9 months ago
Conceptual-level workflow modeling of scientific experiments using NMR as a case study
Background: Scientific workflows improve the process of scientific experiments by making computations explicit, underscoring data flow, and emphasizing the participation of humans...
Kacy K. Verdi, Heidi J. C. Ellis, Michael R. Gryk
BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...