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BMCBI
2010
156views more  BMCBI 2010»
15 years 5 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
145views more  BMCBI 2010»
15 years 5 months ago
JCoDA: a tool for detecting evolutionary selection
Background: The incorporation of annotated sequence information from multiple related species in commonly used databases (Ensembl, Flybase, Saccharomyces Genome Database, Wormbase...
Steven N. Steinway, Ruth Dannenfelser, Christopher...
BMCBI
2010
160views more  BMCBI 2010»
15 years 5 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
149views more  BMCBI 2010»
15 years 5 months ago
KID - an algorithm for fast and efficient text mining used to automatically generate a database containing kinetic information o
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
BMCBI
2010
96views more  BMCBI 2010»
15 years 5 months ago
ModuleOrganizer: detecting modules in families of transposable elements
Background: Most known eukaryotic genomes contain mobile copied elements called transposable elements. In some species, these elements account for the majority of the genome seque...
Sébastien Tempel, Christine Rousseau, Fariz...
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