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158
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BMCBI
2002
126views more  BMCBI 2002»
15 years 4 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
EC
2000
187views ECommerce» more  EC 2000»
15 years 4 months ago
Comparison of Multiobjective Evolutionary Algorithms: Empirical Results
In this paper, we provide a systematic comparison of various evolutionary approaches to multiobjective optimization using six carefully chosen test functions. Each test function i...
Eckart Zitzler, Kalyanmoy Deb, Lothar Thiele
176
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TJS
2002
160views more  TJS 2002»
15 years 4 months ago
Adaptive Optimizing Compilers for the 21st Century
Historically, compilers have operated by applying a fixed set of optimizations in a predetermined order. We call such an ordered list of optimizations a compilation sequence. This...
Keith D. Cooper, Devika Subramanian, Linda Torczon
SIAMCOMP
2010
174views more  SIAMCOMP 2010»
15 years 3 months ago
On the Complexity of Nash Equilibria and Other Fixed Points
We reexamine what it means to compute Nash equilibria and, more generally, what it means to compute a fixed point of a given Brouwer function, and we investigate the complexity o...
Kousha Etessami, Mihalis Yannakakis
BMCBI
2011
14 years 11 months ago
A lightweight, flow-based toolkit for parallel and distributed bioinformatics pipelines
Background: Bioinformatic analyses typically proceed as chains of data-processing tasks. A pipeline, or ‘workflow’, is a well-defined protocol, with a specific structure defin...
Marcin Cieslik, Cameron Mura