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BMCBI
2010
129views more  BMCBI 2010»
15 years 5 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2010
218views more  BMCBI 2010»
15 years 5 months ago
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Background: Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...
Michael Scharfe, Rainer Pielot, Falk Schreiber
BMCBI
2008
87views more  BMCBI 2008»
15 years 5 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
BMCBI
2008
219views more  BMCBI 2008»
15 years 5 months ago
Classification of premalignant pancreatic cancer mass-spectrometry data using decision tree ensembles
Background: Pancreatic cancer is the fourth leading cause of cancer death in the United States. Consequently, identification of clinically relevant biomarkers for the early detect...
Guangtao Ge, G. William Wong
BMCBI
2010
97views more  BMCBI 2010»
15 years 5 months ago
SeqRate: sequence-based protein folding type classification and rates prediction
Background: Protein folding rate is an important property of a protein. Predicting protein folding rate is useful for understanding protein folding process and guiding protein des...
Guan Ning Lin, Zheng Wang, Dong Xu, Jianlin Cheng
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