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BMCBI
2008
78views more  BMCBI 2008»
15 years 5 months ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
BMCBI
2008
121views more  BMCBI 2008»
15 years 5 months ago
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
BMCBI
2008
113views more  BMCBI 2008»
15 years 5 months ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
BMCBI
2008
150views more  BMCBI 2008»
15 years 5 months ago
BibGlimpse: The case for a light-weight reprint manager in distributed literature research
Background: While text-mining and distributed annotation systems both aim at capturing knowledge and presenting it in a standardized form, there have been few attempts to investig...
Thomas Tüchler, Golda Velez, Alexandra Graf, ...
BMCBI
2010
201views more  BMCBI 2010»
15 years 5 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
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