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BMCBI
2010
117views more  BMCBI 2010»
14 years 4 months ago
Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities
Background: Shared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies ar...
Andrew N. Tolopko, John P. Sullivan, Sean D. Erick...
BMCBI
2010
185views more  BMCBI 2010»
14 years 4 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
BIOINFORMATICS
2011
14 years 4 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
BMCBI
2011
14 years 4 months ago
easyDAS: Automatic creation of DAS servers
Background: The Distributed Annotation System (DAS) has proven to be a successful way to publish and share biological data. Although there are more than 750 active registered serv...
Bernat Gel, Andrew M. Jenkinson, Rafael C. Jimenez...
BMCBI
2011
14 years 4 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
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