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» Statistical Approach to Networks-on-Chip
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BMCBI
2010
155views more  BMCBI 2010»
14 years 10 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
89
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BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
103
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BMCBI
2010
147views more  BMCBI 2010»
14 years 10 months ago
Indirect two-sided relative ranking: a robust similarity measure for gene expression data
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
Louis Licamele, Lise Getoor
82
Voted
BMCBI
2010
132views more  BMCBI 2010»
14 years 10 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...