Simulation optimization is rapidly becoming a mainstream tool for simulation practitioners. Simulation optimization is the practice of linking an optimization method with a simula...
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Genetic programming, in conjunction with advanced analytical instruments, is a novel tool for the investigation of complex biological systems at the whole-tissue level. In this stu...
Helen E. Johnson, Richard J. Gilbert, Michael K. W...
In this work we study the complexity of the three-dimensional sandpile avalanches triggered by the addition of two critical configurations. We prove that the algorithmic problem c...