Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia c...
Understanding the sequence-to-structure relationship is a central task in bioinformatics research. Adequate knowledge about this relationship can potentially improve accuracy for ...
Wei Zhong, Jieyue He, Robert W. Harrison, Phang C....