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BIOINFORMATICS
2011
14 years 8 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
SIGMOD
2011
ACM
299views Database» more  SIGMOD 2011»
14 years 7 months ago
Processing theta-joins using MapReduce
Joins are essential for many data analysis tasks, but are not supported directly by the MapReduce paradigm. While there has been progress on equi-joins, implementation of join alg...
Alper Okcan, Mirek Riedewald
DATE
2008
IEEE
78views Hardware» more  DATE 2008»
15 years 11 months ago
Transistor-Specific Delay Modeling for SSTA
SSTA has received a considerable amount of attention in recent years. However, it is a general rule that any approach can only be as accurate as the underlying models. Thus, varia...
Brian Cline, Kaviraj Chopra, David Blaauw, Andres ...
FTML
2008
185views more  FTML 2008»
15 years 4 months ago
Graphical Models, Exponential Families, and Variational Inference
The formalism of probabilistic graphical models provides a unifying framework for capturing complex dependencies among random variables, and building large-scale multivariate stat...
Martin J. Wainwright, Michael I. Jordan
IPMI
2007
Springer
16 years 5 months ago
Shape Modeling and Analysis with Entropy-Based Particle Systems
This paper presents a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization....
Joshua E. Cates, P. Thomas Fletcher, Martin Andrea...