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TCBB
2011
14 years 11 months ago
Semi-Markov Models for Brownian Dynamics Permeation in Biological Ion Channels
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
Vikram Krishnamurthy, Kai Yiu Luk
WSC
2000
15 years 5 months ago
Input modeling using a computer algebra system
Input modeling that involves fitting standard univariate parametric probability distributions is typically performed using an input modeling package. These packages typically fit ...
Diane L. Evans, Lawrence Leemis
SMA
1999
ACM
152views Solid Modeling» more  SMA 1999»
15 years 8 months ago
Fast volume-preserving free form deformation using multi-level optimization
We present an efficient algorithm for preserving the total volume of a solids undergoing free-form deformation using discrete level-of-detail representations. Given the boundary r...
Gentaro Hirota, Renee Maheshwari, Ming C. Lin
SC
1995
ACM
15 years 8 months ago
Distributing a Chemical Process Optimization Application Over a Gigabit Network
We evaluate the impact of a gigabit network on the implementation of a distributed chemical process optimization application. The optimization problem is formulated as a stochasti...
Robert L. Clay, Peter Steenkiste
WSC
1998
15 years 5 months ago
Use of Simulation in Optimization of Maintenance Policies
Selecting an optimum maintenance policy independent of other parameters of the production system does not always yield the overall optimum operating conditions. For instance, high...
Farhad Azadivar, J. Victor Shu