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» Statistical issues in the analysis of Illumina data
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BMCBI
2008
120views more  BMCBI 2008»
13 years 6 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2010
133views more  BMCBI 2010»
13 years 6 months ago
Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
Background: High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explo...
Matthew E. Ritchie, Matthew S. Forrest, Antigone S...
BMCBI
2010
106views more  BMCBI 2010»
13 years 1 months ago
Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data
Background: A key stage for all microarray analyses is the extraction of feature-intensities from an image. If this step goes wrong, then subsequent preprocessing and processing s...
Mike L. Smith, Mark J. Dunning, Simon Tavaré...
BMCBI
2011
13 years 1 months ago
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Background: Illumina’s Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw all...
Matthew E. Ritchie, Ruijie Liu, Benilton Carvalho,...
BMCBI
2010
156views more  BMCBI 2010»
13 years 6 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...