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BMCBI
2006
111views more  BMCBI 2006»
14 years 10 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
KDD
2006
ACM
118views Data Mining» more  KDD 2006»
15 years 10 months ago
Reducing the human overhead in text categorization
Many applications in text processing require significant human effort for either labeling large document collections (when learning statistical models) or extrapolating rules from...
Arnd Christian König, Eric Brill
BMCBI
2007
105views more  BMCBI 2007»
14 years 10 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf
SDM
2010
SIAM
184views Data Mining» more  SDM 2010»
14 years 11 months ago
A Robust Decision Tree Algorithm for Imbalanced Data Sets
We propose a new decision tree algorithm, Class Confidence Proportion Decision Tree (CCPDT), which is robust and insensitive to class distribution and generates rules which are st...
Wei Liu, Sanjay Chawla, David A. Cieslak, Nitesh V...
BMCBI
2007
115views more  BMCBI 2007»
14 years 10 months ago
How accurate and statistically robust are catalytic site predictions based on closeness centrality?
Background: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertic...
Eric Chea, Dennis R. Livesay