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» Statistics of Random Protein Superpositions: p-Values for Pa...

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JCB
2008

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Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment

14 years 10 months ago

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Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...

James O. Wrabl, Nick V. Grishin

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BMCBI
2008

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Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s

14 years 10 months ago

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Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...

Olivier Bastien, Eric Maréchal

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