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85
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BMCBI
2010
134views more  BMCBI 2010»
14 years 9 months ago
Semi-automated screening of biomedical citations for systematic reviews
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...
Byron C. Wallace, Thomas A. Trikalinos, Joseph Lau...
BMCBI
2010
175views more  BMCBI 2010»
14 years 9 months ago
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services
Background: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers. Tools can be made to fle...
Martijn P. van Iersel, Alexander R. Pico, Thomas K...
71
Voted
BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
103
Voted
BMCBI
2007
114views more  BMCBI 2007»
14 years 9 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
BMCBI
2008
133views more  BMCBI 2008»
14 years 9 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...