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BMCBI
2008
128views more  BMCBI 2008»
15 years 6 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
BMCBI
2008
150views more  BMCBI 2008»
15 years 6 months ago
Natural Language Processing in aid of FlyBase curators
Background: Despite increasing interest in applying Natural Language Processing (NLP) to biomedical text, whether this technology can facilitate tasks such as database curation re...
Nikiforos Karamanis, Ruth Seal, Ian Lewin, Peter M...
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong
BMCBI
2006
120views more  BMCBI 2006»
15 years 5 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...