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JCB
2006
114views more  JCB 2006»
13 years 6 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
BMCBI
2007
167views more  BMCBI 2007»
13 years 6 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
NN
2007
Springer
267views Neural Networks» more  NN 2007»
13 years 5 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
ICONIP
2004
13 years 7 months ago
Modeling Gene Regulatory Network in Fission Yeast Cell Cycle Using Hybrid Petri Nets
The complexity of gene regulatory network models stems from the fact that the models should be able to represent continuous, discrete as well as stochastic aspects of gene regulati...
Ranjith Vasireddy, Somenath Biswas
JCB
2002
131views more  JCB 2002»
13 years 6 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong