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ECAI
2010
Springer
15 years 26 days ago
Parallel TBox Classification in Description Logics - First Experimental Results
Abstract. One of the most frequently used inference services of description logic reasoners classifies all named classes of OWL ontologies into a subsumption hierarchy. Due to emer...
Mina Aslani, Volker Haarslev
ALMOB
2008
85views more  ALMOB 2008»
14 years 12 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
BMCBI
2010
125views more  BMCBI 2010»
14 years 12 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
100
Voted
BMCBI
2010
101views more  BMCBI 2010»
14 years 12 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
82
Voted
BMCBI
2010
115views more  BMCBI 2010»
14 years 12 months ago
CONAN: copy number variation analysis software for genome-wide association studies
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
Lukas Forer, Sebastian Schönherr, Hansi Wei&s...