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IJBRA
2008
63views more  IJBRA 2008»
14 years 11 months ago
Protein cavity clustering based on community structure of pocket similarity network
: Functions of a protein are mainly determined by its structure. Surface cavities, also called pockets or clefts, are ordinarily regarded as potentially active sites where the prot...
Zhi-Ping Liu, Ling-Yun Wu, Yong Wang, Xiang-Sun Zh...
BMCBI
2006
111views more  BMCBI 2006»
14 years 12 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
ICPR
2010
IEEE
15 years 3 months ago
Kernel-Based Implicit Regularization of Structured Objects
Weighted graph regularization provides a rich framework that allows to regularize functions defined over the vertices of a weighted graph. Until now, such a framework has been only...
François-Xavier Dupé, Sébastien Bougleux, Luc B...
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 5 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
BMCBI
2008
130views more  BMCBI 2008»
14 years 12 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...