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BMCBI
2007
168views more  BMCBI 2007»
15 years 4 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
125
Voted
BMCBI
2008
133views more  BMCBI 2008»
15 years 4 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
BMCBI
2008
84views more  BMCBI 2008»
15 years 4 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
154
Voted
MICCAI
2010
Springer
15 years 3 months ago
Incorporating Priors on Expert Performance Parameters for Segmentation Validation and Label Fusion: A Maximum a Posteriori STAPL
Abstract. In order to evaluate the quality of segmentations of an image and assess intra- and inter-expert variability in segmentation performance, an Expectation Maximization (EM)...
Olivier Commowick, Simon K. Warfield
GI
2009
Springer
15 years 2 months ago
Component Governance as a Key Factor for IT Business Alignment of Telecommunications Companies
Abstract: Modern telecommunications companies currently undergo remarkable structural changes to be successful in the Next-Generation markets for communications and content product...
Sebastian Reinisch, Uwe Beyer, Robert Mertens