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BMCBI
2006
14 years 9 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
BMCBI
2006
14 years 9 months ago
2006
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
BMCBI
2006
14 years 9 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
CPHYSICS
2006
14 years 9 months ago
2006
A new stochastic method for locating the global minimum of a multidimensional function inside a rectangular hyperbox is presented. A sampling technique is employed that makes use ...
BMCBI
2007
14 years 9 months ago
2007
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...