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119
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BMCBI
2010
123views more  BMCBI 2010»
15 years 2 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
147
Voted
BMCBI
2004
141views more  BMCBI 2004»
15 years 2 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
119
Voted
ACL
1996
15 years 4 months ago
Linguistic Structure as Composition and Perturbation
This paper discusses the problem of learning language from unprocessed text and speech signals, concentrating on the problem of learning a lexicon. In particular, it argues for a ...
Carl de Marcken
APPML
2007
154views more  APPML 2007»
15 years 2 months ago
Comparison of distances between measures
The problem of optimal transportation between a set of sources and a set of wells has become recently the object of new mathematical models generalizing the Monge-Kantorovich prob...
Jean-Michel Morel, Filippo Santambrogio
137
Voted
CDES
2006
97views Hardware» more  CDES 2006»
15 years 4 months ago
Protein Secondary Structure Prediction Accuracy versus Reduction Methods
Predicting protein secondary structure is a key step in determining the 3D structure of a protein that determines its function. The Dictionary of Secondary Structure of Proteins (...
Saad Osman Abdalla Subair, Safaai Deris