Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
Abstract. We have developed a software system that simulates chemotaxis-based cell aggregation in 2D. The model implemented within the system consists of such cell behaviors as che...
Manolya Eyiyurekli, Peter I. Lelkes, David E. Bree...
We present a novel method for detecting and quantifying 3D structure in stacks of microscopic images captured at incremental focal lengths. We express the image data as stochastic...
Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to buil...
Tao Peng, Wei Wang, Gustavo K. Rohde, Robert F. Mu...
We present a pulmonary alveolar epithelial cell model and its simulation results aimed to provide mechanistic insight into biological principles that underlie alveolar morphogenes...
Sean H. J. Kim, Sunwoo Park, Wei Yu, Keith E. Most...