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RECOMB
2010
Springer
15 years 5 months ago
Incremental Signaling Pathway Modeling by Data Integration
Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
Geoffrey Koh, David Hsu, P. S. Thiagarajan
ECAL
2007
Springer
15 years 5 months ago
A Computational System for Investigating Chemotaxis-Based Cell Aggregation
Abstract. We have developed a software system that simulates chemotaxis-based cell aggregation in 2D. The model implemented within the system consists of such cell behaviors as che...
Manolya Eyiyurekli, Peter I. Lelkes, David E. Bree...
3DPVT
2006
IEEE
188views Visualization» more  3DPVT 2006»
15 years 2 months ago
Statistical Inference of Biological Structure and Point Spread Functions in 3D Microscopy
We present a novel method for detecting and quantifying 3D structure in stacks of microscopic images captured at incremental focal lengths. We express the image data as stochastic...
Joseph Schlecht, Kobus Barnard, Barry Pryor
ISBI
2009
IEEE
15 years 5 months ago
Instance-Based Generative Biological Shape Modeling
Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to buil...
Tao Peng, Wei Wang, Gustavo K. Rohde, Robert F. Mu...
CAINE
2007
15 years 12 days ago
Systems Modeling of Alveolar Morphogenesis In Vitro
We present a pulmonary alveolar epithelial cell model and its simulation results aimed to provide mechanistic insight into biological principles that underlie alveolar morphogenes...
Sean H. J. Kim, Sunwoo Park, Wei Yu, Keith E. Most...