Background: Quantifying cell division and death is central to many studies in the biological sciences. The fluorescent dye CFSE allows the tracking of cell division in vitro and i...
Andrew Yates, Cliburn Chan, Jessica Strid, Simon M...
Biological systems consist of many components and interactions between them. In Systems Biology the principal problem is modeling complex biological systems and reconstructing inte...
Marenglen Biba, Stefano Ferilli, Nicola Di Mauro, ...
In this paper we consider a unified framework for parameter estimation problems which arise in a system identification context. In this framework, the parameters to be estimated a...
Kenneth Hsu, Tyrone L. Vincent, Greg Wolodkin, Sun...
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...