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BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
GECCO
2005
Springer
102views Optimization» more  GECCO 2005»
15 years 3 months ago
Latent variable crossover for k-tablet structures and its application to lens design problems
This paper presents the Real-coded Genetic Algorithms for high-dimensional ill-scaled structures, what is called, the ktablet structure. The k-tablet structure is the landscape th...
Jun Sakuma, Shigenobu Kobayashi
GECCO
2003
Springer
123views Optimization» more  GECCO 2003»
15 years 3 months ago
Benefits of Implicit Redundant Genetic Algorithms for Structural Damage Detection in Noisy Environments
A robust structural damage detection method that can handle noisy frequency response function information is discussed. The inherent unstructured nature of damage detection problem...
Anne M. Raich, Tamás Liszkai
RECOMB
1998
Springer
15 years 2 months ago
The hierarchical organization of molecular structure computations
The task of computing molecular structure from combinations of experimental and theoretical constraints is expensive because of the large number of estimated parameters (the 3D co...
Cheng Che Chen, Jaswinder Pal Singh, Russ B. Altma...
BMCBI
2007
134views more  BMCBI 2007»
14 years 10 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...