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COMGEO
2010
ACM
14 years 10 months ago
Approximation algorithm for the kinetic robust K-center problem
Clustering is an important problem and has numerous applications. In this paper we consider an important clustering problem, called the k-center problem. We are given a discrete p...
Sorelle A. Friedler, David M. Mount
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
14 years 9 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
137views more  BMCBI 2006»
14 years 9 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
JAIR
2008
157views more  JAIR 2008»
14 years 9 months ago
Qualitative System Identification from Imperfect Data
Experience in the physical sciences suggests that the only realistic means of understanding complex systems is through the use of mathematical models. Typically, this has come to ...
George Macleod Coghill, Ashwin Srinivasan, Ross D....
JMLR
2008
230views more  JMLR 2008»
14 years 9 months ago
Exponentiated Gradient Algorithms for Conditional Random Fields and Max-Margin Markov Networks
Log-linear and maximum-margin models are two commonly-used methods in supervised machine learning, and are frequently used in structured prediction problems. Efficient learning of...
Michael Collins, Amir Globerson, Terry Koo, Xavier...