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BMCBI
2007
117views more  BMCBI 2007»
15 years 5 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BMCBI
2008
176views more  BMCBI 2008»
15 years 5 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2008
123views more  BMCBI 2008»
15 years 5 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
ECRA
2010
111views more  ECRA 2010»
15 years 5 months ago
RDRP: Reward-Driven Request Prioritization for e-Commerce web sites
Meeting client Quality-of-Service (QoS) expectations proves to be a difficult task for the providers of e-Commerce services, especially when web servers experience overload condit...
Alexander Totok, Vijay Karamcheti
BMCBI
2007
164views more  BMCBI 2007»
15 years 5 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason