A key challenge in architecting a CMP with many cores is maintaining cache coherence in an efficient manner. Directory-based protocols avoid the bandwidth overhead of snoop-based ...
Jason Zebchuk, Vijayalakshmi Srinivasan, Moinuddin...
Application-specific system-on-chip platforms create the opportunity to customize the cache configuration for optimal performance with minimal chip estate. Simulation, in partic...
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
The protein folding problem consists of predicting the functional (native) structure of the protein given its linear sequence of amino acids. Despite extensive progress made in un...