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BMCBI
2006
120views more  BMCBI 2006»
15 years 4 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2007
142views more  BMCBI 2007»
15 years 4 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2006
120views more  BMCBI 2006»
15 years 4 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
JCB
2007
136views more  JCB 2007»
15 years 4 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...
SIGIR
2011
ACM
14 years 7 months ago
Learning online discussion structures by conditional random fields
Online forum discussions are emerging as valuable information repository, where knowledge is accumulated by the interaction among users, leading to multiple threads with structure...
Hongning Wang, Chi Wang, ChengXiang Zhai, Jiawei H...