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» Structured Sparsity in Structured Prediction
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ALMOB
2008
124views more  ALMOB 2008»
15 years 6 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
BMCBI
2010
99views more  BMCBI 2010»
15 years 6 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
CVPR
2005
IEEE
16 years 8 months ago
Multi-Output Regularized Projection
Dimensionality reduction via feature projection has been widely used in pattern recognition and machine learning. It is often beneficial to derive the projections not only based o...
Kai Yu, Shipeng Yu, Volker Tresp