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BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
15 years 2 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
BMCBI
2004
116views more  BMCBI 2004»
15 years 1 months ago
Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure p
Background: A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy mini...
Kishore J. Doshi, Jamie J. Cannone, Christian W. C...
BIOINFORMATICS
2011
14 years 8 months ago
All-atom knowledge-based potential for RNA structure prediction and assessment
Motivation: Over the recent years, the vision that RNA simply serves as information transfer molecule has dramatically changed. The study of the sequence/structure/function relati...
Emidio Capriotti, Tomás Norambuena, Marc A....
RECOMB
2011
Springer
14 years 4 months ago
Rich Parameterization Improves RNA Structure Prediction
Motivation. Current approaches to RNA structure prediction range from physics-based methods, which rely on thousands of experimentally-measured thermodynamic parameters, to machin...
Shay Zakov, Yoav Goldberg, Michael Elhadad, Michal...
BMCBI
2006
108views more  BMCBI 2006»
15 years 1 months ago
Improved Chou-Fasman method for protein secondary structure prediction
Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...
Hang Chen, Fei Gu, Zhengge Huang