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CSB
2002
IEEE
103views Bioinformatics» more  CSB 2002»
15 years 2 months ago
Protein-Based Analysis of Alternative Splicing in the Human Genome
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...
BIOCOMP
2010
14 years 7 months ago
Extraction of Protein Sequence Motifs Information by Bi-Clustering Algorithm
- The activities and function of proteins can potentially be determined by protein sequence motifs. Therefore, obtaining the universally conserved and crossed protein family bounda...
Vincent Yip, Bernard Chen, Sinan Kockara
SDM
2009
SIAM
161views Data Mining» more  SDM 2009»
15 years 6 months ago
Polynomial-Delay and Polynomial-Space Algorithms for Mining Closed Sequences, Graphs, and Pictures in Accessible Set Systems.
In this paper, we study efficient closed pattern mining in a general framework of set systems, which are families of subsets ordered by set-inclusion with a certain structure, pro...
Hiroki Arimura, Takeaki Uno
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
SIGffRid: A tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically drive
Background: Many programs have been developed to identify transcription factor binding sites. However, most of them are not able to infer two-word motifs with variable spacer leng...
Fabrice Touzain, Sophie Schbath, Isabelle Debled-R...