Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
In this paper, we demonstrate that the performance of a motif discovery algorithm can be significantly improved by embedding it into a novel framework that effectively guides the ...
The study of biological networks and network motifs can yield significant new insights into systems biology. Previous methods of discovering network motifs ? network-centric subgra...
— Protein sequence motifs information is crucial to the analysis of biologically significant regions. The conserved regions have the potential to determine the role of the protei...
We present new, general-purpose kernels for protein structure analysis, and describe how to apply them to structural motif discovery and function classification. Experiments show ...