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BMCBI
2010
191views more  BMCBI 2010»
15 years 2 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
BMCBI
2008
202views more  BMCBI 2008»
15 years 2 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2007
176views more  BMCBI 2007»
15 years 2 months ago
The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications
Background: Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to...
J. Christopher Bare, Paul T. Shannon, Amy K. Schmi...
121
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CORR
2010
Springer
137views Education» more  CORR 2010»
15 years 2 months ago
Open Graphs and Monoidal Theories
String diagrams are a powerful tool for reasoning about physical processes, logic circuits, tensor networks, and many other compositional structures. The distinguishing feature of...
Lucas Dixon, Aleks Kissinger
128
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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 2 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
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