We present the design and rationale of a new statically-typed object-oriented language, LOOM. LOOM retains most of the features of the earlier language PolyTOIL. However the subtyp...
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
Thomas Unterthiner, Anne-Kathrin Schultz, Jan Bull...
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
The inclusion of Regular Expressions (REs) is the kernel of any type-checking algorithm for XML manipulation languages. XML applications would benefit from the extension of REs wi...
Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...