Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Comparative genomics has shown that ray-finned fish (Actinopterygii) contain more copies of many genes than other vertebrates. A large number of these additional genes appear to h...
Yves Van de Peer, John Shawe-Taylor, Jayabalan Jos...
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
With the advent of next-generation DNA sequencing machines, there is an increasing need for the development of computational tools that can anchor accurately and expediently the m...