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BMCBI
2006
108views more  BMCBI 2006»
14 years 11 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
15 years 5 months ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel
NAR
2002
80views more  NAR 2002»
14 years 11 months ago
Wanda: a database of duplicated fish genes
Comparative genomics has shown that ray-finned fish (Actinopterygii) contain more copies of many genes than other vertebrates. A large number of these additional genes appear to h...
Yves Van de Peer, John Shawe-Taylor, Jayabalan Jos...
BMCBI
2005
93views more  BMCBI 2005»
14 years 11 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
EDBT
2010
ACM
117views Database» more  EDBT 2010»
15 years 6 months ago
Anchoring millions of distinct reads on the human genome within seconds
With the advent of next-generation DNA sequencing machines, there is an increasing need for the development of computational tools that can anchor accurately and expediently the m...
Tien Huynh, Michail Vlachos, Isidore Rigoutsos