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» Suffix trees for very large genomic sequences
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BMCBI
2007
167views more  BMCBI 2007»
14 years 12 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
BMCBI
2007
151views more  BMCBI 2007»
14 years 12 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
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BMCBI
2004
115views more  BMCBI 2004»
14 years 11 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
BMCBI
2005
113views more  BMCBI 2005»
14 years 11 months ago
PentaPlot: A software tool for the illustration of genome mosaicism
Background: Dekapentagonal maps depict the phylogenetic relationships of five genomes in a visually appealing diagram and can be viewed as an alternative to a single evolutionary ...
Lutz Hamel, Olga Zhaxybayeva, J. Peter Gogarten
VLDB
2007
ACM
128views Database» more  VLDB 2007»
15 years 12 months ago
Periscope/SQ: Interactive Exploration of Biological Sequence Databases
Life science laboratories today have to rely on procedural techniques to store and manage large sequence datasets. Procedural techniques are cumbersome to use and are often very i...
Sandeep Tata, Willis Lang, Jignesh M. Patel