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» Suffix trees for very large genomic sequences
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CIBCB
2007
IEEE
15 years 6 months ago
An Experimental Evaluation of Inversion-and Transposition-Based Genomic Distances through Simulations
— Rearrangements of genes and other syntenic blocks have become a topic of intensive study by phylogenists, comparative genomicists, and computational biologists: they are a feat...
Moulik Kothari, Bernard M. E. Moret
WOB
2004
134views Bioinformatics» more  WOB 2004»
15 years 1 months ago
Reconstruction of Phylogenetic Trees using the Ant Colony Optimization Paradigm
We developed a new approach for the reconstruction of phylogenetic trees using ant colony optimization metaheuristics.Atree is constructed using a fully connected graph and the pro...
Heitor S. Lopes, Mauricio Perretto
RECOMB
2003
Springer
16 years 1 days ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
BMCBI
2006
86views more  BMCBI 2006»
14 years 11 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BMCBI
2010
108views more  BMCBI 2010»
14 years 11 months ago
iGTP: A software package for large-scale gene tree parsimony analysis
Background: The ever-increasing wealth of genomic sequence information provides an unprecedented opportunity for large-scale phylogenetic analysis. However, species phylogeny infe...
Ruchi Chaudhary, Mukul S. Bansal, André Weh...