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BMCBI
2010
243views more  BMCBI 2010»
15 years 17 days ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
91
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BMCBI
2008
95views more  BMCBI 2008»
15 years 17 days ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2008
100views more  BMCBI 2008»
15 years 17 days ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
117
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BMCBI
2008
101views more  BMCBI 2008»
15 years 17 days ago
Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in dros
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Wensheng Zhang, Sige Zou, Jiuzhou Song
BMCBI
2008
98views more  BMCBI 2008»
15 years 17 days ago
PredGPI: a GPI-anchor predictor
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...